Voxel-based cortical thickness measurements in MRI

Voxel-based cortical thickness measurements in MRI

The thickness of the cerebral cortex can provide valuable information about normal and abnormal neuroanatomy. High resolution MRI together with powerful image processing techniques has made it possible to perform these measurements automatically over the whole brain. Here we present a method for automatically generating voxel-based cortical thickness (VBCT) maps. This technique results in maps ...

Segmenting brain sulci for cortical thickness measurements in MRI

C. Hutton, E. De Vita, R. Turner Wellcome Department of Imaging Neuroscience, UCL, London, United Kingdom Synopsis The thickness of the cerebral cortex can provide valuable information about normal and abnormal neuroanatomy. Accurate cortical thickness measurements from brain MRI require precise segmentation of the grey matter. Here we specifically address the problem of extracting the deep cor...

A comparison between voxel-based cortical thickness and voxel-based morphometry in normal aging

The morphology of cortical grey matter is commonly assessed using T1-weighted MRI together with automated computerised methods such as voxel-based morphometry (VBM) and cortical thickness measures. In the presented study we investigate how grey matter changes identified using voxel-based cortical thickness (VBCT) measures compare with local grey matter volume changes identified using VBM. We us...

Cerebral Cortical Thickness Measurements

Assessing the Changes of Cortical Thickness in Alzheimer Disease With MRI Using Freesurfer Software

Introduction: In this study, we intend to determine the correlation between the thickness of the cerebral cortex and the severity of the cognitive disorder in Alzheimer disease (AD). Methods: A total of 20 (14 women and 6 men) patients diagnosed with AD with a Mean age of 72.95 years, and 10 (7 women and 3 men) cognitively normal (CN) subjects with a Mean age of 70.50 years were included in th...